Speaker

　　Chao Cheng,Department of Genetics, Geisel School of Medicine at    Dartmouth, Hanover, New Hampshire 03755, United States of America;
Institute for Quantitative Biomedical Sciences, Norris Cotton
    Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon,
   New Hampshire 03766, United States of America

　　Title

　  Transcriptional regulation inferred from ChIP-seq data

　　Time

　　2013.4.25 3:00-4:00pm            

　　Venue

　　S703

　　Abstract

   Chromatin immunoprecipitation followed by massively parallel  sequencing (ChIP-seq) has been widely used to determine binding sites of
transcription factors (TFs) and to investigate histone modifications in
a genome wide scale. By integrating ChIP-seq data from the ENCODE project
with other data sources such as expression data and TF binding motif  information, we have developed new methods to identify TF target genes,
to predict new human enhancers, to relate TF binding and histone modifications with gene expression, and to construct integrated human regulatory network.
   In this talk, I will explain these new methods and present some case studies. 

　　Affiliation