Abstract |
Cancer is a complex and an evolving disease; each tumor often contains several subpopulations. Omic technologies allow to generating many kinds of molecular data for tumors. Systems biology plays an important role in integrating these data and molecular networks to tickle cancer problems. Cancer hallmark network framework enables qualify, model and predict cancer clinical phenotypes by integrating big data of tumors. This framework helps in developing predictive models for cancer early diagnosis, prognosis, and personalized drug treatment and personalized cancer prevention. |