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scImpute: accurate and robust imputation for single cell RNA-seq data
【2017.7.4 10:30am, S309】

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 2017-06-20 

  Colloquia & Seminars 

  Speaker

Dr.Jingyi Jessica Li, University of California, Los Angeles

  Title

scImpute: accurate and robust imputation for single cell RNA-seq data

  Time

2017.7.4 10:30-11:30

  Venue

S309

  Abstract

The analysis of single-cell RNA-seq (scRNA-seq) data is complicated and biased by excess zero or near zero counts, the so-called dropouts due to the low amounts of mRNA sequenced within individual cells. We introduce scImpute, a statistical method to accurately and robustly impute the dropouts in scRNA-seq data. scImpute is shown as an effective tool to enhance the clustering of cell populations, improve the accuracy of differential expression analysis, and aid the study of gene expression dynamics in time series scRNA-seq experiments      

  Affiliation

 

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